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These findings establish the gut-liver axis as a primary mediator of cadmium toxicity and a potential target for therapeutic intervention (127)

Brain-resident CD4 T cells, entering the CNS during birth, affect CNS development, synaptic pruning, anxiety behaviors, and the transcriptional maturation in microglia and innate immune compartments 66

Additionally, metformin administration significantly increased SOD activity in MIA-induced OA mice, no significant change was observed in GSH-PX levels (Fig

SGLT2i inhibits this high-capacity glucose transporter, SGLT2, in the proximal convoluted tubule and helps the kidneys excrete glucose in the urine to lower blood glucose (196)